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程夏民
阅读次数: 添加时间:2018/12/04 发布:管理员


个人简历


2017至今   欧宝体育官方登录入口,先进化学制造研究院,副教授 

2015-2017  新加坡国立大学,化学与生物分子工程系,Research Fellow

2009-2014  新加坡国立大学,化学系,博士

2006-2009  新加坡南洋理工大学,化学与生物化学系,硕士

1998-2005  南开大学,化学系,学士;元素有机化学研究所,硕士


 


研究方向


化学生物学领域,利用有机合成开发化学工具,进而实现表征并操控生物体系具体包括:

1) 发展新型荧光染料和分子荧光探针并应用于生物成像和活性检测;

2) 应用纳米制备和荧光成像技术研究药物传递;

3) 激酶靶向抑制剂设计、合成与测试。


 


代表性论文


1. CaiX.; Duo Mao, D.; Wang,C.; Kong, D.; Cheng, X.;* and Liu, B.* Multifunctional Liposome: Bright AIEgen-Lipid Conjugate with Strong Photosensitization, Angew. Chem. Int. Ed. (2018), Doi10.1002/anie.201809641. (*共同通讯)

2. Cheng, X.;? Zhang, R.;? Cai, X.; and Liu, B.* A Reusable and Naked-eye Molecular Probe with Aggregation-induced Emission (AIE) Characteristics for Hydrazine Detection. J. Mater. Chem. B, (2017), 53565-3571. (? 共同一作)

3. Yuan, Y.; Xu, S.; Cheng, X.; and Liu, B.* Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation. Angew. Chem. Int. Ed., (2016), 55, 6457–6461.

4. Yuan, Y.;? Zhang, R.;? Cheng, X.;? Xu, S.; and Liu, B.* A FRET Probe with AIEgen as the Energy Quencher: Dual Signal Turn-on for Self-validated Caspase Detection.Chem. Sci., (2016), 7, 4245-4250. (? 共同一作)

5. Cheng, X.; Li, L.; Uttamchandani, M.; Yao, S. Q.*, A Tuned Affinity-Based Staurosporine Probe for In Situ Profiling of Protein Kinases. Chem. Commun., (2014), 50, 2851-2853.

6. Cheng, X.; Li, L.; Uttamchandani, M.; Yao, S. Q.* In Situ Proteome Profiling of C75, a Covalent Bioactive Compound with Potential Anti-cancer Activities. Org. Lett., (2014), 16, 1414-1417

7. Ge, J.; Cheng, X.; Tan, L.P.; Yao, S. Q.*, Ugi Reaction-Assisted Rapid Assembly of Affinity-Based Probes against Potential Protein Tyrosine Phosphatases. Chem. Commun., (2012), 48, 4453-4455.

8. Shi, H.; Cheng, X.; Sze, S.K.; Yao, S. Q.*, Proteome Profiling Reveals Potential Cellular Targets of Staurosporine Using a Clickable Cell-Permeable Probe. Chem. Commun., (2011), 47, 11306-11308.

9. Cheng, X., Liu, X.*, Microwave-enhanced One-pot Synthesis of Diversified 3-Acyl-5-hydroxybenzofurans. J. Combin. Chem. (2007), 9, 906-8.




程夏民 副教授

Email: xiamin@u.nus.edu





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